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Misdiagnosis of ameloblastoma in a patient with clear cell odontogenic carcinoma: a case report

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¹ÚÁ¾Ã¶ ( Park Jong-Cheol ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
±è¼º¿ø ( Kim Seong-Won ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
¹é¿µÀç ( Baek Young-Jae ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
ÀÌÇü±Ù ( Lee Hyeong-Geun ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
À¯¹ÌÇö ( Ryu Mi-Heon ) - Pusan National University School of Dentistry Department of Oral Pathology
Ȳ´ë¼® ( Hwang Dae-Seok ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
±è¿í±Ô ( Kim Uk-Kyu ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery

Abstract


Clear cell odontogenic carcinoma (CCOC), a rare tumor in the head and neck region, displays comparable properties with other tumors clinically and pathologically. In consequence, an incorrect diagnosis may be established. A 51-year-old male patient who was admitted to the Department of Oral and Maxillofacial Surgery at Pusan National University Dental Hospital was initially diagnosed with ameloblastoma via incisional biopsy. However, the excised mass of the patient was observed to manifest histopathological characteristics of ameloblastic carcinoma. The lesion was ultimately diagnosed as clear cell odontogenic carcinoma by the Department of Oral Pathology of Pusan National Dental University. Therefore, segmental mandibulectomy and bilateral neck dissection were performed, followed by reconstruction with fibula free flap and reconstruction plate. Concomitant chemotherapy radiotherapy was not necessary. The patient has been followed up, and no recurrence has occurred 6 months after surgery.

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Neoplasms; Ameloblastoma; Clear cell odontogenic carcinoma

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